Ultrasound-assisted extraction of organic compounds
Researcher: Maria-Loredana Soran
Keywords: extraction, ultrasound, organic compounds.
Description
INCDTIM’s concerns for the extraction of organic compounds from different matrices led to the selection and adaptation in our laboratory of a large number of techniques.
Experimental results obtained, over the years, by the Multifunctional Materials and Biologically Active Compounds research team have led to the conclusion that ultrasound-assisted extraction (UAE) is the most suitable technique for the extraction of organic compounds from various matrices and is scalable. In addition, our research team has experience in optimizing working methods; using statistical methods, it is possible to select the optimal parameters for obtaining preparations with the highest amounts of the organic compound(s) of interest in relation to the raw material used.
Testing different methods and experimental conditions, we concluded that the main advantages of ultrasonic extraction are:
- The technique is environmentally friendly, efficient and economical;
- The use of a minimum volume of solvent and a short working time to obtain a maximum yield of the compounds of interest (in at least 4 times less time the same yield as in extraction by classical methods can be obtained);
- Obtaining high-quality extraction products.
Applications
Areas of application:
extraction of organic compounds from complex organic or inorganic matrices.
Industries: pharmaceutical industry, chemical industry, food supplements industry, agri-food industry, cosmetics industry, environment, health.
Infrastructure
The laboratory has modern equipment for obtaining and characterizing final extracts:
- ultrasonic baths Elmasonic S40H, Transonic T 470/H, Sonorex Digitec;
- Eppendorf 5430R centrifuge (17,000 rpm);
- Rotavapor Heidolph Laborota 4011;
- Shimadzu LC-2010 high-performance liquid chromatograph;
- UV-Vis spectrophotometers for sample analysis Jasco V550, Jasco 6500.
Advantages
INCDTIM offers CDI services based on the ultrasonic extraction method covering a wide range of practical applications.
Before entering into a contractual relationship, we offer consultancy to define the customer/partner’s needs as precisely as possible.
Existing equipment allows us to extract a wide range of compounds.
We have specialized staff, able to cover with the highest professionalism all stages of a contractual collaboration: definition of the problem to be solved, experimental design, data collection, and statistical interpretation of results.
Estimated costs
The cost of a determination is 300-350 lei/test (depending on the complexity) and consists of:
the operating time of the apparatus;
labor, which includes personnel and indirect costs associated with sample preparation operations, analysis and interpretation of results, and preparation of the analysis/research report.