Health and pharma
Our offer is focused on increasing the bioavailability of synthetic or natural active substances by screening novel crystalline forms with increased solubility or by encapsulation in various biocompatible carriers: cyclodextrins, metal-organic structures, solid dispersions, etc. We have developed sensors for various biomarkers as well as functionalized nanosystems for nanomedicine applications.
Cancer biomarker detection using graphene-modified electrode
Authors: Stela Pruneanu, Florina Pogăcean, Lidia Măgerușan, Valentin Mirel
Oxidative DNA damage is responsible for cancer development. The initiation and promotion of malignant cells are associated with chromosomal defects and oncogene activation by free radicals. A common form of lesion is the formation of hydroxylated bases of DNA, considered an important element in chemical carcinogenesis. This detection platform…
Glucose biofunctionalized magnetic nanoparticles
Authors: Alexandrina Nan, Rodica Turcu, Jürgen Liebscher
Owing to their advantageous properties, magnetic nanoparticles featuring diverse coatings are remarkably valuable in the fields of nanomedicine, magnetic separation, organocatalysis, biosensors, and depollution: (i) small size allows easy penetration and removal into/from the media…
Magnetic clusters with controlled properties
Authors: Rodica Turcu, Izabell Crăciunescu
Shape and size controlled magnetic clusters with high magnetic moments in external magnetic field represent an improved alternative to magnetic nanoparticles. They represent platforms for the synthesis of nanocomposites with the most diverse applications that depend on future functionalization…